Currently, I am focused on the structural studies of membrane proteins. I utilize X-ray crystallography and cryoEM in order to study the structures of enzymes involved in biosynthesis of lipoproteins in bacteria. This research is carried out in prof. Martin Caffrey lab at Trinity College Dublin.
My PhD focues on a structural characterization of enzymes from the histidine biosynthetic pathway in plants. These studies were complemented by enzymatic and computational analyses aimed at identifying novel pathway inhibitors and tracing evolutionary history of these enzymes.
As the saying goes, "You are what you eat". The safety of soil, and consequently the food grown in it, is crucial for human well-being. Therefore, together with my supervisor, Prof. Miłosz Ruszkowski, I co-authored a series of papers addressing issues of food safety and herbicide resistance. Our work covers seven of the eight enzymes involved in the histidine pathway, providing insights into their structure, activity, regulation, and phylogeny.
This work became the subject of my article-based doctoral dissertation, Structural Biology of the Histidine Biosynthetic Pathway in Plants, available here.
My name is Wojtek, and currently, I am a research fellow in the group of Membrane Structural and Functional Biology at the Trinity College in Dublin, Ireland.
In 2024, I completed my PhD in the Department of Structural Biology of Eukaryotes at the Institute of Bioorganic Chemistry, Polish Academy of Sciences in Poznan, Poland. My PhD project was focused on the structural and functional characterization of the histidine biosynthetic pathway in plants.
However, my passion for science started much earlier. I graduated in biology and neurobiology, focusing on insect physiology and neuro-endocrine system. As a student and an active member of the scientific club, I was interested in the effects of cannabinoid oil, plant alkaloids, and FMRFamide-related peptides on insect physiology. These results have been published in a peer-review journal and presented at serveral scientific conferences.
Membrane Structural and Functional Biology Group
School of Biochemistry & Immunology
Trinity Biomedical Sciences Institute
Trinity College Dublin
Dublin, Ireland