The articles below are arranged according to the consecutive actions of the HISN1-8 enzymes in the histidine biosynthetic pathway
HISN2
Witek W., Śliwiak J., Ruszkowski M. (2021) Structural and mechanistic insights into the bifunctional HISN2 enzyme catalyzing the second and third steps of histidine biosynthesis in plants, Scientific Reports 11(1):9647,
HISN5
Witek W., Sliwiak J., Rawski M., Ruszkowski M. (2024) Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting, Frontiers in Plant Science 15;15:1343980, https://doi.org/10.3389/fpls.2024.1343980
HISN6
Rutkiewicz M., Nogues I., Witek W., Angelaccio S., Contestabile R., Ruszkowski M. (2023) Insights into the substrate specificity, structure, and dynamics of plant histidinol-phosphate aminotransferase (HISN6), Plant Physiology and Biochemistry 196:759-773, https://doi.org/10.1016/j.plaphy.2023.02.017
Marciniak P., Witek W., Szymczak M., Pacholska-Bogalska J., Chowański S., Kuczer M., Rosiński G. (2020) FMRFamide-Related Peptides Signaling Is Involved in the Regulation of Muscle Contractions in Two Tenebrionid Beetles, Frontiers in Physiology 12;11:456, https://doi.org/10.3389/fphys.2020.00456
Witek W., Ragin W., Tran H. L., Połomska E., Podlewski M., Pawłowicz A., Cioch-Biniaś A., Woś A., Andrałojć W., Szachniuk M., Ruszkowski M. (2024) Postępy biologii strukturalnej – jak zobaczyć cząsteczki życia?, Postępy Biochemii, https://doi.org/10.18388/pb.2017_
HISN1
Ruszkowski M. (2018) Guarding the gateway to histidine biosynthesis in plants: Medicago truncatula ATP- phosphoribosyltransferase in relaxed and tense states, Biochemical Journal (2018) 475 2681–2697,
https://doi.org/10.1042/BCJ20180289
HISN7
Ruszkowski M., Dauter Z. (2016) Structural Studies of Medicago truncatula Histidinol Phosphate Phosphatase from Inositol Monophosphatase Superfamily Reveal Details of Penultimate Step of Histidine Biosynthesis in Plants, The Journal of Biological Chemistry, vol. 291, no. 19, pp. 9960–9973,
https://doi.org/10.1074/jbc.M115.708727
HISN8
Ruszkowski M., Dauter Z. (2017) Structures of Medicago truncatula L-Histidinol Dehydrogenase Show Rearrangements Required for NAD+ Binding and the Cofactor Positioned to Accept a Hydride, Scientific Reports, 7: 10476, https://doi.org/10.1038/s41598-017-10859-0